The movie revolves around Easwaran alias E (Jiiva), an orphan brought up in the musty, teeming slums of Chennai by an old woman. For him, money is the thing in life, so he does anything for that. He comes across Jothy (Nayantara), a bar dancer, who settles down in the same locality. After a few encounters, they get acquainted with each other. E's simple ways attract Jothy.
Coming to know of his past, Jothy tries desperately to correct his ways and set him on the right path. Meanwhile, Dr. Ramakrishnan (Ashish Vidyarthi) takes up the task of testing a medicine devised by a foreign company, which may come handy in killing people in thousands, especially during times of war. Ramakrishnan chooses Jothy's sister and E's grandmother as specimens for the test. He cashes in on the ignorance to slum-dwellers. Things take a turn, when E rescues Ramakrishnan from a murder bid by Nellai Mani (Pasupathy).
A sequence of events brings Nellai Mani and E together. Without knowing his motive, E hides him in a secret place and decides to hand him over to Ramakrishnan for a huge sum. Slowly, E gets attracted by good ways of Nellai Mani. Through him, E comes to know of Ramakrishnan's ulterior motives. Nellai Mani, a revolutionary fighting for a cause, tries to bring about a change in E's heart. Succeeding in his attempt, Nellai Mani lays down his life leaving E to complete his task. The rest is all about E's show all the way in putting an end to Ramakrishnan and his evil ways.
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